Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.68 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 1/20 | 0.50 |
| ▸ | LDHB | P07195 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390486 | 0.84 | L3MBTL1 (0.48) | L3MBTL1LDHALDHBALDH1A1KMT2A | |
| SCHEMBL8585874 | 0.84 | FFAR1 (0.52) | L3MBTL1KMT2ATDP1LMNAGAA | |
| SCHEMBL8699595 | 0.83 | KMT2A (0.61) | L3MBTL1ALDH1A1KMT2ANPC1MEN1 | |
| SCHEMBL22281426 | 0.82 | GSK3B (0.61) | L3MBTL1GSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL25241435 | 0.80 | GPR88 (0.51) | L3MBTL1LDHALDHBKMT2AMEN1 | |
| SCHEMBL27146207 | 0.80 | AKR1C3 (0.54) | L3MBTL1ALDH1A1KMT2ATDP1MEN1 | |
| SCHEMBL5161471 | 0.80 | L3MBTL1 (0.64) | L3MBTL1GSK3BALDH1A1KMT2ATDP1 | |
| SCHEMBL9148324 | 0.80 | L3MBTL1 (0.73) | L3MBTL1ALDH1A1KMT2ATDP1NPC1 | |
| SCHEMBL11522648 | 0.80 | L3MBTL1 (0.61) | L3MBTL1GSK3BHDAC3HDAC4HDAC1 | |
| SCHEMBL7976858 | 0.80 | L3MBTL1 (0.61) | L3MBTL1GSK3BALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331073-B1 | BENZHYDRYLAMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5051526-A | Reagents for solid phase synthesis of polypeptides | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4965405-A | INTERMEDIATE FOR POLYPEPTIDE SYNTHESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0331073-A2 | Benzhydrylamine derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |