Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 10/20 | 0.45 |
| ▸ | PRCP | P42785 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7518909 | 0.71 | — | — | |
| SCHEMBL1881008 | 0.71 | FKBP1A (0.61) | FKBP1A | |
| SCHEMBL26291061 | 0.70 | FKBP1A (0.60) | FKBP1ATSHR | |
| SCHEMBL12869918 | 0.70 | FKBP1A (0.60) | FKBP1ATSHR | |
| SCHEMBL13099455 | 0.70 | FKBP1A (0.60) | FKBP1ATSHR | |
| SCHEMBL8323846 | 0.70 | TSHR (0.47) | FKBP1ATSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL28250011 | 0.69 | CHRNB2 (0.54) | FKBP1ATSHR | |
| SCHEMBL6380145 | 0.69 | FKBP1A (0.47) | FKBP1ATSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL29845766 | 0.69 | FKBP1A (0.47) | FKBP1ATSHRCYP2C19SMN1; SMN2 | |
| SCHEMBL9475212 | 0.69 | FKBP1A (0.59) | FKBP1APRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |