Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CASP2 | P42575 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058235 | 0.83 | MAPT (0.38) | RAB9AALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL5702000 | 0.82 | PI4KB (0.40) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9058236 | 0.80 | SMN1; SMN2 (0.35) | ALDH1A1LMNASMN1; SMN2GAAMAPT | |
| SCHEMBL8594445 | 0.79 | GRM1 (0.37) | KDM4EALDH1A1SMN1; SMN2GAAMAPT | |
| SCHEMBL6953240 | 0.76 | KMT2A (0.46) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8699278 | 0.74 | KMT2A (0.42) | KDM4ETHRBMAPK1ALDH1A1LMNA | |
| SCHEMBL8700078 | 0.73 | MAPT (0.56) | KDM4ETHRBMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8699435 | 0.72 | RBP4 (0.49) | KDM4EMAPK1ALDH1A1LMNAGAA | |
| SCHEMBL8699464 | 0.72 | MAPT (0.37) | KDM4ENPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9266046 | 0.72 | GAA (0.52) | KDM4ENPC1RAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |