Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058235 | 0.84 | MAPT (0.38) | SMN1; SMN2RAB9AMAPTGAAALDH1A1 | |
| SCHEMBL8699764 | 0.82 | KDM4E (0.46) | KDM4ESMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL9058236 | 0.81 | SMN1; SMN2 (0.35) | SMN1; SMN2MAPTGAALMNAALDH1A1 | |
| SCHEMBL8594445 | 0.80 | GRM1 (0.37) | KDM4ESMN1; SMN2MAPTGAAHPGD | |
| SCHEMBL6953240 | 0.77 | KMT2A (0.46) | KDM4ESMN1; SMN2HTTNPC1RAB9A | |
| SCHEMBL8699464 | 0.76 | MAPT (0.37) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8699278 | 0.75 | KMT2A (0.42) | KDM4ESMN1; SMN2HTTMAPTGAA | |
| SCHEMBL7626369 | 0.73 | MAPT (0.45) | KDM4ESMN1; SMN2HTTRAB9AMAPT | |
| SCHEMBL9266046 | 0.73 | GAA (0.52) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8699897 | 0.72 | GAA (0.41) | KDM4ESMN1; SMN2HTTRAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1073637-B1 | 3-(AMINO- OR AMINOALKYL)PYRIDINONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF HIV RELATED DISEASES | CENTRE NAT RECH SCIENT (FR) | 2006-08-02 | — | — | EP | disclosed |
| US-6683079-B2 | REVERSE TRANSCRIPTASE INHIBITORS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2004-01-27 | — | — | US | disclosed |
| US-20030125340-A1 | Reverse transcriptase inhibitors | CENTRE NATIONAL DE LA RECHERCHE SCIENT. (FR) | 2003-07-03 | — | — | US | disclosed |
| US-6451822-B1 | 3-(Amino- or aminoalkyl)pyridinone derivatives and their use for the treatment of HIV related diseases | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-09-17 | — | — | US | disclosed |
| EP-1073637-A1 | 3-(AMINO- OR AMINOALKYL)PYRIDINONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF HIV RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2001-02-07 | — | — | EP | disclosed |
| WO-1999055676-A1 | 3-(AMINO- OR AMINOALKYL)PYRIDINONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF HIV RELATED DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125340-A1 | Reverse transcriptase inhibitors | QTRT1, RTF2, POLR1A | PI4KB 1720/4885KDM4E 534/4885SMN1; SMN2 3825/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.