Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702000 | 0.84 | PI4KB (0.40) | MAPTSMN1; SMN2GAAALOX15ALDH1A1 | |
| SCHEMBL8699764 | 0.83 | KDM4E (0.46) | MAPTSMN1; SMN2GAAALDH1A1RAB9A | |
| SCHEMBL9058236 | 0.82 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2GAAALOX15ALDH1A1 | |
| SCHEMBL8594445 | 0.81 | GRM1 (0.37) | MAPTSMN1; SMN2GAAALOX15ALDH1A1 | |
| SCHEMBL6953240 | 0.78 | KMT2A (0.46) | MAPTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL8699278 | 0.76 | KMT2A (0.42) | MAPTSMN1; SMN2GAAALDH1A1POLB | |
| SCHEMBL8699464 | 0.74 | MAPT (0.37) | MAPTSMN1; SMN2ALDH1A1POLBGRM1 | |
| SCHEMBL9266046 | 0.74 | GAA (0.52) | MAPTSMN1; SMN2GAAALOX15ALDH1A1 | |
| SCHEMBL8699897 | 0.73 | GAA (0.41) | MAPTSMN1; SMN2GAAALOX15ALDH1A1 | |
| SCHEMBL9846287 | 0.73 | GAA (0.33) | SMN1; SMN2GAAPOLBGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |