SCHEMBL281673

SCHEMBL281673

Oc1ccc2c(c1)OCC2

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.56
MAOB P27338 1/20 0.56
CA2 P00918 1/20 0.50
CA5A P35218 1/20 0.50
DRD2 P14416 1/20 0.50
DRD1 P21728 1/20 0.50
DRD4 P21917 1/20 0.50
DRD5 P21918 1/20 0.50
DRD3 P35462 1/20 0.50
CYP3A4 P08684 1/20 0.48
ESR2 Q92731 3/20 0.47
ESR1 P03372 2/20 0.47
TTR P02766 1/20 0.47
PRKCI P41743 1/20 0.43
CHRNA7 P36544 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM1 P11229 1/20 0.40
CHRNB2 P17787 1/20 0.40
CHRM3 P20309 1/20 0.40
CHRNA4 P43681 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL15153543 0.89 MAOA (0.51) MAOAMAOBCA2CA5ADRD2
SCHEMBL8699804 0.88 MAOA (0.49) MAOAMAOBCA2CA5ADRD2
SCHEMBL29598243 0.88 MAOA (0.49) MAOAMAOBCA2CA5ADRD2
Hydrochloric Acid SCHEMBL28232988 0.86 MAOA (0.47) MAOAMAOBCA2CA5ADRD2
Formaldehyde SCHEMBL27689991 0.83 MAOA (0.49) MAOAMAOBCA2CA5ADRD2
SCHEMBL281830 0.83 PRKCI (0.56) MAOAMAOBCYP3A4ESR2ESR1
SCHEMBL26777072 0.80 MAOA (0.64) MAOAMAOBDRD2DRD1DRD4
Ethane SCHEMBL28204754 0.79 PRKCI (0.53) MAOAMAOBDRD2DRD1DRD4
SCHEMBL8344049 0.79 MAOA (0.45) MAOAMAOBDRD2DRD1DRD4
SCHEMBL19141318 0.76 CHRM2 (0.41) DRD2DRD3PRKCICHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112679680-B Bionic piezoresistive material, preparation method thereof and wearable bionic piezoresistive sensor 苏州经贸职业技术学院 2022-12-20 CN claimed
CN-113122062-A Quantum dot ink and preparation method of quantum dot film TCL集团股份有限公司 2021-07-16 CN claimed
CN-112679680-A Bionic piezoresistive material, preparation method thereof and wearable bionic piezoresistive sensor 苏州经贸职业技术学院 2021-04-20 CN claimed
US-5730962-A Depigmenting cosmetic or dermatologic composition containing a benzofuran derivative and its use in depigmentating skin L'OREAL (FR) 1998-03-24 US claimed
EP-0524108-B1 Use of derivatives of benzofurane as depigmentation agents in cosmetic or dermatological compositions OREAL (FR) 1995-06-07 EP claimed
EP-0088024-B1 PYRIDO(3,4-C)PSORALENES, PREPARATION, USE IN COSMETOLOGY AND IN MEDICINE AND COMPOSITIONS CONTAINING THEM INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1986-09-17 EP claimed
CN-119192107-B Quenching fluorescent probe for specifically detecting gold ions and preparation method and application thereof 南京林业大学 2025-12-02 CN disclosed
US-12421193-B2 GPR52 modulators and methods of use NEUROCRINE BIOSCIENCES, INC. (US) 2025-09-23 US disclosed
CN-119192107-A Quenching fluorescent probe for specifically detecting gold ions and preparation method and application thereof 南京林业大学 2024-12-27 CN disclosed
CN-119192105-A Process for the preparation of 6-benzofuranols 安徽昊帆生物有限公司 2024-12-27 CN disclosed
US-12090146-B2 Substituted-pyridinyl compounds and uses thereof BIONOMICS LIMITED (AU) 2024-09-17 US disclosed
EP-3853216-B1 3-[2-(PHENOXY)-4-PYRIDYL]-IMIDAZOLIDINE-2,4-DIONE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DYSFUNCTION AND CNS DISORDERS BIONOMICS LTD (AU) 2024-09-11 EP disclosed
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS IDORSIA PHARMACEUTICALS LTD (CH) 2024-06-27 US disclosed
EP-0411513-A1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-02-06 EP disclosed
EP-0132130-B1 AROYL BENZOFURAN AND BENZOTHIOPHENE ACETIC AND PROPIONIC ACIDS PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM SYNTEX (U.S.A.) INC. (US) 1990-03-07 EP disclosed
US-4838924-A NONPHYTOTOXIC MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-13 US disclosed
US-4816473-A ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS SYNTEX (U.S.A.) INC. (US) 1989-03-28 US disclosed
US-4780480-A ANALGESICS, ANTIINFLAMMATORY AGENTS SYNTEX (U.S.A.) INC. (US) 1988-10-25 US disclosed
EP-0132130-A2 Aroyl benzofuran and benzothiophene acetic and propionic acids processes for their production and pharmaceutical compositions containing them SYNTEX (U.S.A.) INC. (US) 1985-01-23 EP disclosed
US-4002647-A INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1977-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12090146-B2 Substituted-pyridinyl compounds and uses thereof GABRE, GAP43, GRIN2A MAOA 698/4885MAOB 659/4885CA2 2156/4885
US-20240208992-A1 MACROCYCLES AS CFTR MODULATORS CFTR, PKD1, ARRB1 MAOA 4169/4885MAOB 3987/4885CA2 2641/4885
US-12421193-B2 GPR52 modulators and methods of use GPR52, GPR68, GPR35 MAOA 1015/4885MAOB 947/4885CA2 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.