Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7628968 | 0.76 | MEN1 (0.46) | NPC1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7626374 | 0.72 | MEN1 (0.40) | NPC1MAPTSMN1; SMN2LMNATSHR | |
| SCHEMBL25279182 | 0.72 | POLB (0.45) | NPC1MAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8699309 | 0.72 | TSHR (0.39) | NPC1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6956149 | 0.69 | ALDH1A1 (0.44) | NPC1MAPTALDH1A1SMN1; SMN2HTT | |
| SCHEMBL25274599 | 0.69 | KDM4E (0.48) | NPC1MAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL25229438 | 0.69 | KMT2A (0.53) | ALDH1A1SMN1; SMN2LMNAHTTTSHR | |
| SCHEMBL8088990 | 0.68 | MAPT (0.39) | NPC1MAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL23090393 | 0.68 | KDM4E (0.47) | NPC1MAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8699109 | 0.68 | TDP1 (0.41) | MAPTALDH1A1LMNATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |