Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2006064 | 0.76 | SLC13A5 (0.41) | TDP1SLC13A5TSHRNPSR1ALDH1A1 | |
| SCHEMBL713040 | 0.76 | PTGIR (0.51) | TDP1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL21598413 | 0.75 | TDP1 (0.40) | TDP1SLC13A5NPSR1ALDH1A1GAA | |
| SCHEMBL10994586 | 0.74 | LMNA (0.50) | TDP1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL16812908 | 0.73 | APLNR (0.43) | TDP1SLC13A5ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17329609 | 0.73 | HTT (0.41) | KMT2ATSHRNPSR1ALDH1A1GAA | |
| SCHEMBL7628968 | 0.72 | MEN1 (0.46) | TDP1KMT2AMEN1TSHRNPSR1 | |
| SCHEMBL16487052 | 0.72 | KMT2A (0.53) | TDP1KMT2AALDH1A1GAAMAPT | |
| SCHEMBL24683219 | 0.71 | APLNR (0.44) | KMT2AMEN1TSHRALDH1A1GAA | |
| SCHEMBL6114094 | 0.71 | SLC13A5 (0.36) | TDP1SLC13A5ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |