Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.42 |
| ▸ | FLT4 | P35916 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325335 | 0.87 | ALDH1A1 (0.47) | SMN1; SMN2LMNAALDH1A1PPARAFLT1 | |
| SCHEMBL11779341 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2LMNAALDH1A1CA2CA5A | |
| SCHEMBL295414 | 0.79 | SMN1; SMN2 (0.57) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11848402 | 0.77 | AKR1C3 (0.55) | TSHRCASP1SMN1; SMN2LMNAFLT1 | |
| SCHEMBL6416634 | 0.77 | ALDH1A1 (0.44) | TSHRSMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL10477056 | 0.76 | KDM4E (0.67) | TSHRCASP1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3418753 | 0.76 | ALDH1A1 (0.71) | TSHRCASP1SMN1; SMN2ALDH1A1MYC | |
| SCHEMBL1786859 | 0.75 | ALDH1A1 (0.43) | CASP1LMNAALDH1A1PPARAALPL | |
| SCHEMBL7979793 | 0.75 | ALPL (0.48) | SMN1; SMN2ALDH1A1PPARAALPLALPI | |
| SCHEMBL9740555 | 0.75 | AKR1C3 (0.45) | TSHRSMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5801120-A | HERBICIDES FOR CONTROLLING WEEDS | SANDOZ LTD. (CH) | 1998-09-01 | — | — | US | disclosed |
| US-5700762-A | HERBICIDES | SANDOZ LTD. (CH) | 1997-12-23 | — | — | US | disclosed |
| US-5608101-A | HERBICIDES | NOVARTIS AG (CH) | 1997-03-04 | — | — | US | disclosed |
| US-5089046-A | Herbicides or miticide | SANDOZ LTD. (CH) | 1992-02-18 | — | — | US | disclosed |
| CN-1038093-A | To organic compound with about the improvement of organic compound | SANDOZ LTD (CH) | 1989-12-20 | — | — | CN | disclosed |
| EP-0338992-A2 | Substituted aryl and heteroaryl bicyclodiones | SANDOZ AG (CH) | 1989-10-25 | — | — | EP | disclosed |
| EP-0336898-A2 | Substituted aryl or heteroaryl diones | SANDOZ AG (CH) | 1989-10-11 | — | — | EP | disclosed |