Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357275 | 0.89 | EPHX2 (0.48) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL19602224 | 0.86 | ALDH1A1 (0.49) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6357782 | 0.85 | NLRP3 (0.52) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6355171 | 0.84 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6355594 | 0.82 | PPARG (0.50) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL8409841 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6357278 | 0.81 | EPHX2 (0.52) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6359228 | 0.80 | PPARG (0.47) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL12998282 | 0.78 | MEN1 (0.53) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 | |
| SCHEMBL6485462 | 0.78 | LMNA (0.42) | ALDH1A1KMT2AMEN1L3MBTL1NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731454-A | Allosteric modifiers of hemoglobin useful for decreasing oxygen affinity and preserving oxygen carrying capability of stored blood | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1998-03-24 | — | — | US | disclosed |
| US-5705521-A | Use of allosteric hemoglobin modifiers in combination with radiation therapy to treat carcinogenic tumors | THE CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1998-01-06 | — | — | US | disclosed |
| US-5591892-A | CARBOXYALKOXYPHENYL SUBSTITUTED INDANES | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5432191-A | Ring-substituted phenoxymethyl /or substituted methyl/ carboxylates | THE CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1995-07-11 | — | — | US | disclosed |