Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.50 |
| ▸ | CSF1R | P07333 | 10/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035770 | 0.71 | ALOX5 (0.45) | ALOX5 | |
| SCHEMBL8783921 | 0.69 | ALOX5 (0.67) | ALOX5 | |
| SCHEMBL10902395 | 0.69 | ICMT (0.53) | — | |
| SCHEMBL8787991 | 0.69 | ALOX5 (0.76) | ALOX5 | |
| SCHEMBL8413218 | 0.69 | ALOX5 (0.53) | ALOX5 | |
| SCHEMBL8783759 | 0.69 | ALOX5 (0.71) | ALOX5 | |
| Hydrochloric Acid SCHEMBL8783874 | 0.68 | ALOX5 (0.70) | ALOX5 | |
| Hydrochloric Acid SCHEMBL8783222 | 0.68 | ALOX5 (0.65) | ALOX5 | |
| SCHEMBL8696022 | 0.68 | ALOX5 (0.77) | ALOX5 | |
| SCHEMBL8783957 | 0.68 | ALOX5 (0.66) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753682-A | Imidazole lipoxygenase inhibitors | PFIZER INC. (US) | 1998-05-19 | — | — | US | disclosed |