Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802549 | 0.76 | ALOX5 (0.55) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10382761 | 0.74 | DRD2 (0.39) | CYP3A4CYP2D6CYP2C19ADRA1A | |
| SCHEMBL8698136 | 0.74 | ALOX5 (0.56) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8695817 | 0.73 | ALOX5 (0.55) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8701045 | 0.71 | ALOX5 (0.47) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8700427 | 0.71 | ALOX5 (0.50) | ALOX5 | |
| SCHEMBL8696022 | 0.70 | ALOX5 (0.77) | ALOX5 | |
| SCHEMBL8702203 | 0.70 | ALOX5 (0.57) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6026185 | 0.69 | DRD2 (0.43) | CYP3A4 | |
| SCHEMBL8694707 | 0.69 | ALOX5 (0.44) | ALOX5GRM5CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0703913-A1 | IMIDAZOLE LIPOXYGENASE INHIBITORS | PFIZER (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1994029299-A1 | IMIDAZOLE LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1994-12-22 | — | — | WO | disclosed |