Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ATIC | P31939 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | CFD | P00746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27452727 | 0.85 | KAT6A (0.33) | KAT6AHSD11B1F10PRSS1PRSS2 | |
| SCHEMBL27476255 | 0.82 | KAT6A (0.33) | KAT6AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8705969 | 0.80 | BTK (0.33) | KAT6ABTKATICHSD11B1F10 | |
| SCHEMBL8705383 | 0.78 | KISS1R (0.35) | KAT6A | |
| SCHEMBL8700431 | 0.78 | KAT6A (0.36) | KAT6AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8699108 | 0.77 | SERPINE1 (0.39) | PRSS1PRSS2PRSS3 | |
| SCHEMBL8703824 | 0.76 | KAT6A (0.46) | KAT6AF10 | |
| Guanidine SCHEMBL8700429 | 0.76 | CHRM2 (0.36) | F10PRSS1PRSS2PRSS3CHRM2 | |
| SCHEMBL8703300 | 0.75 | HRH3 (0.33) | KAT6AATICHSD11B1 | |
| SCHEMBL27361121 | 0.75 | PFKFB3 (0.36) | KAT6AF10PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |