Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | LTA4H | P09960 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1846156 | 0.78 | LTA4H (0.56) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL249581 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL9974888 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL249579 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL249580 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL11398297 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL11398300 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL6081694 | 0.75 | LTA4H (0.60) | KDM1AMAOALTA4HFUCA1USP2 | |
| SCHEMBL8706953 | 0.74 | KDM1A (0.40) | KDM1AMAOALTA4HMAOB | |
| SCHEMBL2197651 | 0.72 | KDM1A (0.58) | KDM1AMAOAMAOBFUCA1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | claimed |
| US-5750549-A | ANTIINFLAMMATORY AGENTS OR ANALGESICS | MERCK & CO., INC. (US) | 1998-05-12 | — | — | US | disclosed |