Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398300 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL6081694 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL11398297 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL249580 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL249581 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL249579 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL1846156 | 0.97 | LTA4H (0.56) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7247232 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7177046 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7247234 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202910-B2 | Compositions and methods for treatment of infectious disease | SEQUELLA, INC. (US) | 2012-06-19 | — | — | US | disclosed |
| US-7842729-B2 | Anti tubercular drug: compositions and methods | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-11-30 | — | — | US | disclosed |
| US-7456222-B2 | Anti tubercular drug: compositions and methods | SEQUELLA, INC. (US) | 2008-11-25 | — | — | US | disclosed |