Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.60 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9974888 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL11398300 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL6081694 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL11398297 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL249580 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL249581 | 1.00 | LTA4H (0.60) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL1846156 | 0.97 | LTA4H (0.56) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7247232 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7177046 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B | |
| SCHEMBL7247234 | 0.85 | ADRA2A (0.52) | LTA4HKDM1AMAOAFUCA1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | VAIDYA NITEEN A (US) | 2012-02-16 | — | — | US | claimed |
| US-7820715-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-26 | — | — | US | claimed |
| US-20080090907-A1 | Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | claimed |
| US-20070185346-A1 | Kit for automated resolving agent selection and method thereof | VAIDYA NITEEN A | 2007-08-09 | — | — | US | claimed |
| EP-1741697-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | claimed |
| EP-0590685-B1 | Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative | KURARAY CO (JP) | 1996-05-29 | — | — | EP | claimed |
| US-5371282-A | Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative | KURARAY CO., LTD. (JP) | 1994-12-06 | — | — | US | claimed |
| EP-0590685-A1 | Process for optical resolution of (+)-cis-4-aminocyclopent-2-en-1-carboxylic acid derivative | KURARAY CO., LTD. (JP) | 1994-04-06 | — | — | EP | claimed |
| US-5280122-A | Resolution of 2-benzyl-4-piperidone-succinic acid | PFIZER INC. (US) | 1994-01-18 | — | — | US | claimed |
| EP-0298480-B1 | PROCESS FOR THE OPTICAL RESOLUTION OF (+)-CIS OR (+)-TRANS-PERMETHRIC ACID | Kuraray Co., Ltd. (JP) | 1992-10-14 | — | — | EP | claimed |
| US-4845272-A | Process for the optical resolution of (±)-cis or (±)-trans-permethric acid | KURARAY CO., LTD. (JP) | 1989-07-04 | — | — | US | claimed |
| JP-56133244-A | — | — | None | — | — | JP | disclosed |
| JP-58029753-A | — | — | None | — | — | JP | disclosed |
| JP-11043475-A | — | — | None | — | — | JP | disclosed |
| JP-1016747-A | — | — | None | — | — | JP | disclosed |
| EP-0084856-A1 | 5,6,7-Trinor-4, 8-inter-m-phenylene prostaglandin I2 derivatives | TORAY INDUSTRIES, INC. (JP) | 1983-08-03 | — | — | EP | disclosed |
| JP-S5829753-A | OPTICAL RESOLUTION OF (+-)-3-ENDO-BENZAMIDE-5-NORBORNENE-2-ENDO-CARBOXYLIC ACID | NOHIRA HIROYUKI | 1983-02-22 | — | — | JP | disclosed |
| JP-S56133244-A | OPTICAL RESOLUTION OF (+-)-TRANS-CHRYSANTHEMUM-MONO- CARBOXYLIC ACID | NOHIRA HIROYUKI | 1981-10-19 | — | — | JP | disclosed |
| JP-S5533440-A | OPTICALLY ACTIVE BENZYL(2-HYDROXYMETHYLCYCLOHEXYL) AMINE, ITS PREPARATION, AND ITS OPTICAL RESOLUTION | NOHIRA HIROYUKI | 1980-03-08 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090907-A1 | Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine | TAS2R5, FFAR2, HRH2 | LTA4H 2303/4885KDM1A 2966/4885MAOA 262/4885 |
| US-20120041225-A1 | KIT FOR AUTOMATED RESOLVING AGENT SELECTION AND METHOD THEREOF | ACKR3, KIT, C3AR1 | LTA4H 55/4885KDM1A 3874/4885MAOA 2076/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | LTA4H 1391/4885KDM1A 807/4885MAOA 3263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.