Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.35 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.35 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19812300 | 0.86 | TAAR1 (0.37) | HTR1ATAAR1RIPK1NPSR1MEN1 | |
| SCHEMBL9853837 | 0.86 | L3MBTL1 (0.44) | ADRA2AADRA2BADRA2CNISCHSLC6A2 | |
| SCHEMBL388941 | 0.85 | TAAR1 (0.56) | TAAR1 | |
| SCHEMBL7438547 | 0.85 | NPSR1 (0.36) | TAAR1RIPK1NPSR1 | |
| SCHEMBL19812305 | 0.83 | L3MBTL1 (0.40) | TAAR1CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL16113242 | 0.83 | TAAR1 (0.35) | TAAR1CSNK1A1CSNK1DPRKCDPAK1 | |
| SCHEMBL7240943 | 0.82 | RIPK1 (0.36) | TAAR1RIPK1 | |
| SCHEMBL2325955 | 0.82 | RIPK1 (0.36) | TAAR1RIPK1 | |
| SCHEMBL15283292 | 0.82 | RIPK1 (0.36) | TAAR1RIPK1NPSR1 | |
| SCHEMBL2675279 | 0.82 | ELANE (0.38) | TAAR1RIPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |