Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700617 | 0.86 | ADRA2A (0.41) | NPSR1NISCHADRA2AADRA2BADRA2C | |
| SCHEMBL15283292 | 0.85 | RIPK1 (0.36) | NPSR1RIPK1PREPDRD2IDO1 | |
| SCHEMBL2325955 | 0.85 | RIPK1 (0.36) | RIPK1PREPDRD2IDO1 | |
| SCHEMBL7240943 | 0.85 | RIPK1 (0.36) | RIPK1PREPDRD2IDO1 | |
| SCHEMBL30039264 | 0.84 | CYP4F2 (0.36) | KDM4ESLC6A2SLC6A4RIPK1DRD2 | |
| SCHEMBL6943654 | 0.84 | CYP4F2 (0.36) | KDM4ESLC6A2SLC6A4RIPK1DRD2 | |
| SCHEMBL3149357 | 0.84 | RIPK1 (0.35) | SLC6A2SLC6A4SLC6A3RIPK1PREP | |
| SCHEMBL9944001 | 0.83 | HTT (0.34) | L3MBTL1MAPTNPSR1KDM4ERIPK1 | |
| SCHEMBL7134633 | 0.82 | BACE1 (0.43) | MAPTHPGDRIPK1PREPIDO1 | |
| Bromide SCHEMBL4071853 | 0.82 | RIPK1 (0.34) | L3MBTL1MAPTKMT2ARIPK1PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422329-A1 | Substituted dibenzofurans and methods of using same | Euro-Celtique S.A. (LU) | 1991-04-17 | — | — | EP | disclosed |