Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849370 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL975264 | 0.78 | FDPS (0.42) | TSHR | |
| SCHEMBL6565224 | 0.76 | MAPT (0.36) | TSHR | |
| SCHEMBL381408 | 0.74 | MMP1 (0.37) | TSHR | |
| SCHEMBL1464011 | 0.74 | — | — | |
| SCHEMBL16397973 | 0.72 | — | — | |
| SCHEMBL11540857 | 0.72 | TRPV1 (0.31) | — | |
| SCHEMBL8523714 | 0.72 | DNM1 (0.40) | TSHR | |
| SCHEMBL15121451 | 0.72 | MMP1 (0.35) | TSHR | |
| SCHEMBL15121410 | 0.72 | MMP1 (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |