Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697702 | 0.83 | ALDH1A1 (0.37) | ACSS2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL7074513 | 0.79 | ACSS2 (0.53) | ACSS2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL27787906 | 0.70 | ACSS2 (0.50) | ACSS2ALDH1A1RAB9AKDM4E | |
| SCHEMBL13359036 | 0.69 | ACSS2 (0.49) | ACSS2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL8694187 | 0.68 | AGPAT2 (0.39) | ACSS2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL23139483 | 0.68 | RORC (0.56) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL8695229 | 0.68 | ALDH1A1 (0.72) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL916307 | 0.67 | MAPT (0.45) | ALDH1A1HPGDRAB9ANPC1MAPT | |
| SCHEMBL10238329 | 0.66 | ACSS2 (0.52) | ACSS2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL28490404 | 0.66 | ALDH1A1 (0.50) | ALDH1A1HPGDRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018768-A1 | HERBICIDAL 3-(BICYCLIC NITROGEN-CONTAINING HETEROCYCLE)-SUBSTITUTED-1-METHYL-6-TRIFLUOROMETHYLURACILS | FMC CORPORATION (US) | 1998-05-07 | — | — | WO | disclosed |
| US-5661108-A | CONTROLLING PLANT GROWTH | FMC CORPORATION (US) | 1997-08-26 | — | — | US | disclosed |