Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700661 | 0.85 | SLC9A1 (0.43) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8705014 | 0.83 | PSEN1 (0.43) | LMNAALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL8705723 | 0.83 | PSEN1 (0.40) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8704076 | 0.82 | PSEN1 (0.36) | ALDH1A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8447922 | 0.82 | SLC9A1 (0.52) | — | |
| SCHEMBL8707552 | 0.82 | SLC9A1 (0.46) | GAALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8705466 | 0.81 | HTT (0.41) | GAALMNAKDM4EALDH1A1KMT2A | |
| SCHEMBL8699344 | 0.81 | GAA (0.42) | GAALMNAKDM4EALDH1A1HPGD | |
| SCHEMBL8701748 | 0.80 | PSEN1 (0.39) | KMT2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8704528 | 0.80 | PSEN1 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |