Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.37 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 2/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707552 | 0.89 | SLC9A1 (0.46) | GAALMNASLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8705442 | 0.88 | SLC9A1 (0.37) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8700586 | 0.83 | SLC9A1 (0.50) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8703472 | 0.82 | KDM4E (0.41) | GAASLC9A1SLC9A3SLC9A2KDM4E | |
| SCHEMBL8704148 | 0.82 | EED (0.40) | GAASLC9A1SLC9A3SLC9A2KDM4E | |
| SCHEMBL8703757 | 0.82 | PKM (0.40) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8703455 | 0.82 | MAPT (0.41) | GAALMNASLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8705466 | 0.82 | HTT (0.41) | GAALMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8700375 | 0.81 | SLC9A1 (0.38) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8444870 | 0.81 | SLC9A1 (0.57) | SLC9A1SLC9A3SLC9A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |