Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.39 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.39 |
| ▸ | SLC9A2 | Q9UBY0 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701738 | 0.88 | SLC9A1 (0.49) | EEDNR1I2SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8700586 | 0.86 | SLC9A1 (0.50) | NR1I2SLC9A1SLC9A3SLC9A2KDM4E | |
| SCHEMBL8703472 | 0.85 | KDM4E (0.41) | SLC9A1SLC9A3SLC9A2GAAKDM4E | |
| SCHEMBL8703455 | 0.85 | MAPT (0.41) | NR1I2SLC9A1SLC9A3SLC9A2GAA | |
| SCHEMBL8703757 | 0.85 | PKM (0.40) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8700375 | 0.84 | SLC9A1 (0.38) | SLC9A1SLC9A3SLC9A2KDM4EKMT2A | |
| SCHEMBL8446474 | 0.82 | SLC9A1 (0.58) | SLC9A1SLC9A3SLC9A2 | |
| SCHEMBL8699798 | 0.82 | CFTR (0.39) | SLC9A1SLC9A3SLC9A2KMT2A | |
| SCHEMBL8700491 | 0.82 | SLC9A1 (0.37) | EEDSLC9A1SLC9A3SLC9A2KDM4E | |
| SCHEMBL8700680 | 0.82 | GAA (0.38) | SLC9A1SLC9A3SLC9A2GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753680-A | Heterocyclyl-benzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-05-19 | — | — | US | disclosed |