Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700846 | 0.91 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8700950 | 0.89 | GPR4 (0.42) | — | |
| SCHEMBL8702146 | 0.80 | — | — | |
| SCHEMBL28055956 | 0.77 | AGTR1 (0.40) | AGTR1AGTR2 | |
| SCHEMBL8707753 | 0.73 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL244556 | 0.73 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL7414046 | 0.70 | — | — | |
| SCHEMBL8705385 | 0.68 | — | — | |
| SCHEMBL243509 | 0.67 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL15939889 | 0.66 | GPR4 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |