SCHEMBL8700846

SCHEMBL8700846

Cc1cc(C)c2nc(C3CC3)n(Cc3ccc(C4c5ccccc5CC4C(=O)O)s3)c2n1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 2/20 0.40
AGTR2 P50052 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8700760 0.91 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL8702146 0.88
SCHEMBL8700950 0.79 GPR4 (0.42)
SCHEMBL244556 0.77 AGTR1 (0.41) AGTR1AGTR2
SCHEMBL245008 0.72 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL2876441 0.72 AGTR1 (0.38) AGTR1AGTR2
SCHEMBL8706908 0.70 AGTR1 (0.37) AGTR1AGTR2
SCHEMBL7421373 0.68
Benzenesulfonamide SCHEMBL5031361 0.67 AGTR1 (0.36) AGTR1AGTR2
SCHEMBL8999035 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5789415-A Azacyclic-heterocyclic compounds as angiotension II receptor antagonists PFIZER INC. (US) 1998-08-04 US disclosed