SCHEMBL8700767

SCHEMBL8700767

CC(=O)N1COCN(Cc2ccc(Cl)nc2)C1=N[N+](=O)[O-]

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CASP6 P55212 1/20 0.45
CHRNB2 P17787 3/20 0.45
CHRNA4 P43681 3/20 0.45
ALDH1A1 P00352 2/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45
ATM Q13315 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
MAPT P10636 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
CHRNA1 P02708 2/20 0.41
CHRNA7 P36544 2/20 0.41
CHRNA3 P32297 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8701693 0.90 CASP6 (0.44) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL8697320 0.89 CASP6 (0.43) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL9069702 0.87 CASP6 (0.48) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL7996080 0.86 CASP6 (0.53) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL7996083 0.86 CASP6 (0.53) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL8701610 0.86 CASP6 (0.43) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL29578091 0.86 CHRNB2 (0.49) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL9403865 0.86 CHRNB2 (0.49) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL236408 0.86 CHRNB2 (0.49) CASP6CHRNB2CHRNA4ALDH1A1KMT2A
SCHEMBL8703917 0.85 CASP6 (0.42) CASP6CHRNB2CHRNA4ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998006710-A1 SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION NOVARTIS AG (CH) 1998-02-19 WO claimed
WO-1998006710-A1 SUBSTITUTED 4-NITROIMINO-PERHYDRO-1,3,5-OXADIAZINE DERIVATIVES, THEIR USE AS PESTICIDES AND INTERMEDIATES FOR THEIR PREPARATION NOVARTIS AG (CH) 1998-02-19 WO disclosed