Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.44 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578091 | 1.00 | CHRNB2 (0.49) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL9403865 | 1.00 | CHRNB2 (0.49) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL7172981 | 0.90 | CHRNB2 (0.48) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL29578118 | 0.87 | CHRM1 (0.36) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL420648 | 0.87 | CHRM1 (0.36) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL234081 | 0.86 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL237645 | 0.86 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL237657 | 0.86 | CHRNB2 (0.35) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL8700767 | 0.86 | CASP6 (0.45) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL9826625 | 0.85 | CHRNB2 (0.55) | CHRNB2CHRNA4ALDH1A1SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120022053-A1 | Oxadiazine Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2012-01-26 | — | — | US | claimed |
| US-7836630-B2 | Method of protecting seeds treated with a phytotoxic agent | MONSANTO TECHNOLOGY LLC (US) | 2010-11-23 | — | — | US | claimed |
| US-20100179196-A1 | COMPOSITIONS AND METHODS FOR DEPLOYING A TRANSGENIC REFUGE AS A SEED BLEND | PERSHING JAY C | 2010-07-15 | — | — | US | claimed |
| EP-1566996-B1 | METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT | MONSANTO TECHNOLOGY LLC (US) | 2009-11-11 | — | — | EP | claimed |
| US-20070219188-A1 | Oxadiazine Derivatives | SYNGENTA CROP PROTECTION, INC. (US) | 2007-09-20 | — | — | US | claimed |
| WO-2004049778-A9 | METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT | MONSANTO TECHNOLOGY LLC (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050197251-A1 | Method of controlling the release of agricultural active ingredients from treated plant seeds | MONSANTO TECHNOLOGY, L.L.C. (US) | 2005-09-08 | — | — | US | claimed |
| EP-1566996-A1 | METHOD OF PROTECTING SEEDS TREATED WITH A PHYTOTOXIC AGENT | Monsanto Technology LLC (US) | 2005-08-31 | — | — | EP | claimed |
| US-6884755-B2 | Pesticidal composition | SYNGENTA CROP PROTECTION, INC. (US) | 2005-04-26 | — | — | US | claimed |
| US-20040259732-A1 | Treatment of plants and plant propagation materials with an antioxidant to improve plant health and/or yield | MONSANTO TECHNOLOGY, L.L.C. | 2004-12-23 | — | — | US | claimed |
| US-20030018992-A1 | Method for reducing pest damage to corn by treating transgenic corn seeds with pesticide | MONSANTO TECHNOLOGY, L.L.C. | 2003-01-23 | — | — | US | claimed |
| WO-2002080675-A1 | TREATED PLANT SEEDS WITH CONTROLLED RELEASE OF ACTIVE AGENTS | MONSANTO TECHNOLOGY, LLC (US) | 2002-10-17 | — | — | WO | claimed |
| US-20020134012-A1 | Method of controlling the release of agricultural active ingredients from treated plant seeds | MONSANTO TECHNOLOGY, L.L.C. | 2002-09-26 | — | — | US | claimed |
| US-20020115565-A1 | Seed treatment with combinations of insecticides | MONSANTO TECHNOLOGY, L.L.C. | 2002-08-22 | — | — | US | claimed |
| WO-2002030205-A2 | TREATMENT OF TRANSGENIC CORN SEEDS WITH PESTICIDES | MONSANTO TECHNOLOGY, LLC (US) | 2002-04-18 | — | — | WO | claimed |
| WO-2002028186-A2 | SEED TREATMENT WITH COMBINATIONS OF INSECTICIDES | MONSANTO TECHNOLOGY, LLC (US) | 2002-04-11 | — | — | WO | claimed |
| EP-0874549-B1 | METHOD OF CONTROLLING FISH PARASITES | NOVARTIS AG (CH) | 2001-12-12 | — | — | EP | claimed |
| US-5852012-A | Oxadiazine derivatives | NOVARTIS CORPORATION (US) | 1998-12-22 | — | — | US | claimed |
| WO-1997015192-A1 | 1,3,5-OXADIAZINES AS MOLLUSCICIDES | NOVARTIS AG (CH) | 1997-05-01 | — | — | WO | claimed |
| EP-0580553-A2 | Oxadiazine derivatives | CIBA-GEIGY AG (CH) | 1994-01-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219188-A1 | Oxadiazine Derivatives | CBR3, AOC3, AOC2 | CHRNB2 1127/4885CHRNA4 1839/4885ALDH1A1 1694/4885 |
| US-20120022053-A1 | Oxadiazine Derivatives | CBR3, AOC3, AOC2 | CHRNB2 1127/4885CHRNA4 1839/4885ALDH1A1 1694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.