Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 11/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14496264 | 0.94 | MCL1 (0.72) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL7770325 | 0.92 | MCL1 (0.59) | MCL1ALDH1A1MAPTADORA3SMN1; SMN2 | |
| SCHEMBL8700922 | 0.88 | MCL1 (0.53) | MCL1ADORA3CHEK1SMN1; SMN2LTB4R | |
| SCHEMBL4630405 | 0.87 | MCL1 (0.60) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL30614602 | 0.87 | MCL1 (0.60) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL7772127 | 0.80 | MCL1 (0.49) | MCL1ALDH1A1MAPTHPGDADORA3 | |
| SCHEMBL28441178 | 0.80 | ALDH1A1 (0.50) | MCL1ALDH1A1HPGDADORA3ECE1 | |
| SCHEMBL14008675 | 0.79 | FAAH (0.52) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL17595320 | 0.79 | MCL1 (0.71) | MCL1ALDH1A1MAPTHPGDRECQL | |
| SCHEMBL14151460 | 0.78 | ALDH1A1 (0.59) | MCL1ALDH1A1MAPTHPGDADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |