Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772127 | 0.92 | MCL1 (0.49) | MCL1ADORA3KDM4EMEN1KMT2A | |
| SCHEMBL8700788 | 0.88 | MCL1 (0.64) | MCL1ADORA3LTB4RCHEK1SMN1; SMN2 | |
| SCHEMBL14496264 | 0.85 | MCL1 (0.72) | MCL1ADORA3 | |
| SCHEMBL7770325 | 0.80 | MCL1 (0.59) | MCL1ADORA3KDM4EMEN1KMT2A | |
| SCHEMBL7850867 | 0.76 | ABL1 (0.47) | MCL1ADORA3KDM4EKMT2AABL1 | |
| SCHEMBL8600130 | 0.75 | TERT (0.47) | MCL1ADORA3KDM4EKMT2AABL1 | |
| SCHEMBL8596986 | 0.75 | ABL1 (0.44) | MCL1ADORA3KDM4EABL1ABCB1 | |
| SCHEMBL14008675 | 0.75 | FAAH (0.52) | MCL1KDM4EGAASMN1; SMN2 | |
| SCHEMBL4630405 | 0.74 | MCL1 (0.60) | MCL1ADORA3KDM4EMEN1GAA | |
| SCHEMBL28473632 | 0.74 | PARP1 (0.51) | MCL1ADORA3KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760191-A | Macrocyclic complexing agents and targeting immunoreagents useful in therapeutic and diagnostic compositions and methods | NYCOMED IMAGING AS (NO) | 1998-06-02 | — | — | US | disclosed |