Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.36 |
| ▸ | FNTB | P49356 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.31 |
| ▸ | ACLY | P53396 | 2/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702011 | 0.88 | FLT1 (0.34) | FNTAFNTBFLT1FLT4KDR | |
| SCHEMBL8700590 | 0.87 | CYP19A1 (0.44) | FNTAFNTBMAPTHPGDCYP19A1 | |
| SCHEMBL8702874 | 0.85 | IDO1 (0.35) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL8697636 | 0.81 | CYP19A1 (0.45) | FNTAFNTBMAPTHPGDGABRG2 | |
| SCHEMBL8697624 | 0.79 | CYP19A1 (0.50) | MAPTHPGDCYP19A1CYP17A1 | |
| SCHEMBL8703068 | 0.78 | CYP19A1 (0.36) | FNTAFNTBGRM5MAPTCYP19A1 | |
| SCHEMBL8698363 | 0.75 | CYP19A1 (0.45) | MAPTHPGDCYP19A1CYP17A1CYP11B1 | |
| SCHEMBL8700262 | 0.75 | CYP19A1 (0.42) | FNTAFNTBGRM5FLT1FLT4 | |
| SCHEMBL8697780 | 0.72 | CYP19A1 (0.40) | MAPTHPGDCYP19A1CYP17A1CYP11B1 | |
| SCHEMBL8699139 | 0.72 | CYP19A1 (0.38) | MAPTHPGDCYP19A1CYP17A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |