Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | FNTA | P49354 | 2/20 | 0.36 |
| ▸ | FNTB | P49356 | 2/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700537 | 0.79 | CYP19A1 (0.47) | CYP19A1KCNH2CYP3A4 | |
| SCHEMBL8700849 | 0.75 | FNTA (0.36) | CYP19A1FNTAFNTBKCNH2FLT1 | |
| SCHEMBL8700590 | 0.74 | CYP19A1 (0.44) | CYP19A1FNTAFNTBKCNH2CYP11B1 | |
| SCHEMBL8697944 | 0.71 | CYP3A4 (0.43) | CYP19A1FNTAFNTBFLT1FLT4 | |
| SCHEMBL8697489 | 0.70 | CYP3A4 (0.49) | CYP19A1FNTAFNTBFLT1FLT4 | |
| SCHEMBL8697941 | 0.67 | CYP11B1 (0.34) | FLT1FLT4KDRCYP11B1CYP11B2 | |
| SCHEMBL8702186 | 0.67 | CYP19A1 (0.47) | CYP19A1TSHR | |
| SCHEMBL8697485 | 0.67 | CYP11B1 (0.34) | FLT1FLT4KDRCYP11B1CYP11B2 | |
| SCHEMBL8698606 | 0.65 | ATM (0.32) | — | |
| SCHEMBL8702011 | 0.65 | FLT1 (0.34) | CYP19A1FNTAFNTBFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |