Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 2/20 | 0.32 |
| ▸ | FNTB | P49356 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700849 | 0.88 | FNTA (0.36) | FLT1FLT4KDRMAPTHPGD | |
| SCHEMBL8698363 | 0.87 | CYP19A1 (0.45) | MEN1KMT2AMAPTHPGDCYP19A1 | |
| SCHEMBL8697636 | 0.82 | CYP19A1 (0.45) | MAPTHPGDFNTAFNTBCYP19A1 | |
| SCHEMBL8700053 | 0.78 | CYP19A1 (0.51) | MAPTHPGDKDM4EFNTAFNTB | |
| SCHEMBL8697611 | 0.77 | ALDH1A1 (0.33) | LMNACYP19A1ALDH1A1MYC | |
| SCHEMBL8700590 | 0.75 | CYP19A1 (0.44) | MEN1KMT2AMAPTHPGDFNTA | |
| SCHEMBL8702874 | 0.74 | IDO1 (0.35) | MEN1KMT2AKDM4ELMNACYP19A1 | |
| SCHEMBL8697780 | 0.73 | CYP19A1 (0.40) | MEN1KMT2AMAPTHPGDCYP19A1 | |
| SCHEMBL8700623 | 0.69 | CYP19A1 (0.64) | MEN1KMT2AMAPTHPGDCYP19A1 | |
| SCHEMBL8696966 | 0.68 | MAPT (0.40) | MEN1KMT2AMAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | disclosed |