Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792173 | 0.92 | POLB (0.62) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL6757232 | 0.88 | LMNA (0.62) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL4110878 | 0.87 | LMNA (0.64) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL1299032 | 0.86 | IDO1 (0.67) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL9518720 | 0.83 | POLB (0.59) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL5742159 | 0.81 | PDE10A (0.57) | POLBRAB9APDE10A | |
| SCHEMBL6753966 | 0.78 | POLB (0.64) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL6448765 | 0.77 | POLB (0.67) | POLBNPC1RAB9ALMNAIDO1 | |
| SCHEMBL230157 | 0.77 | POLB (0.84) | POLBNPC1RAB9APDE10ACHRM1 | |
| SCHEMBL2948984 | 0.76 | POLB (0.65) | POLBNPC1RAB9ALMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |