Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4110878 | 0.98 | LMNA (0.64) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL6753966 | 0.90 | POLB (0.64) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL6448765 | 0.88 | POLB (0.67) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL8700939 | 0.88 | POLB (0.57) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL2948984 | 0.87 | POLB (0.65) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL4111972 | 0.85 | IDO1 (0.70) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL6759257 | 0.84 | IDO1 (0.68) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL5792173 | 0.80 | POLB (0.62) | LMNAPOLBNPC1RAB9AIDO1 | |
| SCHEMBL230157 | 0.79 | POLB (0.84) | POLBNPC1RAB9ADDAH1CHRM1 | |
| SCHEMBL1825671 | 0.78 | IDO1 (0.79) | LMNAPOLBNPC1RAB9AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6712262-B2 | BENZIMIDAZOLE AND IODINE COMPOUNDS | TAMURAKAKEN CORPORATION (JP) | 2004-03-30 | — | — | US | disclosed |