Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716519 | 0.83 | PSMB8 (0.59) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL26382710 | 0.80 | PSMB8 (0.56) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8701312 | 0.80 | PSMB8 (0.62) | PSMB8KEAP1DAOKDM4EALDH1A1 | |
| SCHEMBL8701782 | 0.75 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL8699552 | 0.75 | PSMB8 (0.68) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL3237564 | 0.74 | TAAR1 (0.64) | DAOMAOBKDM4EALDH1A1GAA | |
| SCHEMBL27434246 | 0.73 | TAAR1 (0.47) | DAOMAOBKDM4EALDH1A1GAA | |
| SCHEMBL8703483 | 0.71 | ALDH1A1 (0.52) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL15727620 | 0.70 | PSMB8 (0.56) | PSMB8KEAP1KDM4EALDH1A1GAA | |
| SCHEMBL9885484 | 0.70 | IDO1 (0.54) | DAOMAOBLTA4HTAAR1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |