Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.68 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12716519 | 0.90 | PSMB8 (0.59) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL8701782 | 0.84 | PSMB8 (0.68) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL779231 | 0.81 | PSMB8 (1.00) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL8703483 | 0.81 | ALDH1A1 (0.52) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL8701312 | 0.78 | PSMB8 (0.62) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL8700992 | 0.75 | PSMB8 (0.43) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL9367728 | 0.73 | MEN1 (0.79) | PSMB8ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8701281 | 0.73 | PSMB8 (0.64) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL8698519 | 0.73 | PSMB8 (0.45) | PSMB8KEAP1ALDH1A1KDM4EGAA | |
| SCHEMBL777690 | 0.71 | PSMB8 (1.00) | PSMB8KEAP1ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |