Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615489 | 0.79 | ALDH1A1 (0.60) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL5681552 | 0.78 | CYP1A2 (0.46) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL119090 | 0.78 | CYP1A2 (0.56) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL29360084 | 0.78 | CYP1A2 (0.56) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL130782 | 0.76 | ALDH1A1 (0.45) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL8695870 | 0.76 | CYP2A6 (0.42) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL7905083 | 0.76 | CYP1A2 (0.56) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL21360527 | 0.76 | HSD17B10 (0.42) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL5750656 | 0.76 | ALDH1A1 (0.56) | HSD17B10TSHRHIF1AHPGDMAPK1 | |
| SCHEMBL14596475 | 0.76 | HSD17B10 (0.42) | HSD17B10TSHRHIF1AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840684-A | Glycopeptide antibiotic derivatives | ELI LILLY AND COMPANY (US) | 1998-11-24 | — | — | US | disclosed |