Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701152 | 1.00 | FDPS (0.50) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4459921 | 0.85 | FDPS (0.49) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4453114 | 0.85 | FDPS (0.49) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4453124 | 0.85 | FDPS (0.49) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4455160 | 0.83 | FDPS (0.46) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4455148 | 0.83 | FDPS (0.46) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL4456265 | 0.83 | FDPS (0.46) | FDPSRAB9ANPC1LMNATSHR | |
| SCHEMBL7879989 | 0.80 | HSPA1A (0.58) | RAB9ANPC1LMNATSHRAURKA | |
| SCHEMBL7879986 | 0.80 | HSPA1A (0.58) | RAB9ANPC1LMNATSHRAURKA | |
| Hydrochloric Acid SCHEMBL9183800 | 0.79 | HSPA1A (0.57) | RAB9ANPC1LMNATSHRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| CN-1121713-A | serine derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1996-05-01 | — | — | CN | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |