Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.58 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.58 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.58 |
| ▸ | HSPA2 | P54652 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7879986 | 1.00 | HSPA1A (0.58) | HSPA1AHSPA5HSPA9HSPA2KDM4E | |
| Hydrochloric Acid SCHEMBL9183800 | 0.99 | HSPA1A (0.57) | HSPA1AHSPA5HSPA9HSPA2KDM4E | |
| SCHEMBL6960135 | 0.82 | HSPA1A (0.60) | HSPA1AHSPA5HSPA9HSPA2KDM4E | |
| SCHEMBL6960139 | 0.82 | HSPA1A (0.60) | HSPA1AHSPA5HSPA9HSPA2KDM4E | |
| SCHEMBL8701152 | 0.80 | FDPS (0.50) | KDM4EPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL8701148 | 0.80 | FDPS (0.50) | KDM4EPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL4453124 | 0.79 | FDPS (0.49) | KDM4EPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL4459921 | 0.79 | FDPS (0.49) | KDM4EPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL4453114 | 0.79 | FDPS (0.49) | KDM4EPKMSMN1; SMN2LMNATSHR | |
| SCHEMBL2501414 | 0.77 | PPARG (0.54) | L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177571-B1 | REMOVING HEAVY METALS, SELECTED FROM PALLADIUM, TIN AND NICKEL, FROM HEAVY METAL COMPLEXES WITH THIAZOLE COMPOUNDS IN AQUEOUS OR ALCOHOLIC SOLUTION, BY PRECIPITATION AS SULFIDES | ZAMBON GROUP S.P.A. (IT) | 2001-01-23 | — | — | US | claimed |