Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695519 | 0.81 | STS (0.49) | STSMAPTMEN1KMT2ATP53 | |
| SCHEMBL8695762 | 0.81 | TP53 (0.44) | STSMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL8695530 | 0.79 | F2 (0.46) | STSMAPTSMN1; SMN2GAAMEN1 | |
| SCHEMBL8696210 | 0.77 | STS (0.45) | STSMAPTMEN1KMT2ATP53 | |
| SCHEMBL7445442 | 0.77 | F2 (0.52) | STSF2GPR119 | |
| SCHEMBL8698733 | 0.75 | F2 (0.47) | STSMAPTTHRBMEN1KMT2A | |
| SCHEMBL8698765 | 0.75 | HTR6 (0.46) | STSMEN1KMT2AF2 | |
| SCHEMBL8698820 | 0.73 | STS (0.46) | STSMAPTMEN1KMT2AF2 | |
| SCHEMBL7602868 | 0.71 | F2 (0.56) | STSMAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8695575 | 0.71 | STS (0.46) | STSMAPTMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |