Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696586 | 0.88 | TDP1 (0.51) | TDP1CA1CA2CA7CA9 | |
| SCHEMBL9464191 | 0.81 | TDP1 (0.70) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL93708 | 0.80 | CA1 (0.66) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL4382418 | 0.80 | CA1 (0.66) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL93709 | 0.80 | CA1 (0.66) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL4385964 | 0.80 | CA1 (0.66) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8427417 | 0.79 | TDP1 (0.58) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL304176 | 0.79 | TDP1 (0.78) | TDP1CASP1ALDH1A1KMT2AAPP | |
| SCHEMBL29053751 | 0.78 | TDP1 (0.66) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| Bicarbonate SCHEMBL7699565 | 0.77 | TDP1 (0.75) | TDP1CASP1ALDH1A1KMT2AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |