Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8427652 | 0.92 | ADRB2 (0.55) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL8429393 | 0.85 | ALDH1A1 (0.53) | ADRB2ADRB1ADRB3ALDH1A1KMT2A | |
| SCHEMBL23406378 | 0.82 | TDP1 (0.54) | TDP1MAPTLPAR1ADRB2ADRB1 | |
| SCHEMBL9464191 | 0.81 | TDP1 (0.70) | TDP1MAPTLPAR1ADRB2ADRB1 | |
| SCHEMBL8701193 | 0.79 | TDP1 (0.58) | TDP1MAPTLPAR1ADRB2ADRB1 | |
| SCHEMBL29053751 | 0.78 | TDP1 (0.66) | TDP1MAPTLPAR1ADRB2ADRB1 | |
| SCHEMBL14866787 | 0.78 | ALDH1A1 (0.45) | TDP1ALDH1A1KMT2A | |
| SCHEMBL8696586 | 0.77 | TDP1 (0.51) | TDP1MAPTLPAR1ADRB2ADRB1 | |
| SCHEMBL3185725 | 0.76 | TDP1 (0.68) | TDP1MAPTADRB2ADRB1ADRB3 | |
| SCHEMBL18585442 | 0.76 | PDE4A (0.39) | TDP1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773949-B1 | D-MANNOSE OR XYLITOL ESTERS AND THEIR USE AS DRUGS | ASSOCIAZIONE DI VOLONTARIATO P (IT) | 1999-11-10 | — | — | EP | claimed |
| US-5830872-A | THERAPY FOR BLOOD DISORDERS | L'ASSOCIAZIONE DI VOLONTARIATO "PRO LA FONDAZIONE FUTURO SENZA THALASSEMIA" (IT) | 1998-11-03 | — | — | US | claimed |
| US-5830872-A | THERAPY FOR BLOOD DISORDERS | L'ASSOCIAZIONE DI VOLONTARIATO "PRO LA FONDAZIONE FUTURO SENZA THALASSEMIA" (IT) | 1998-11-03 | — | — | US | disclosed |