Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701193 | 0.88 | TDP1 (0.58) | TDP1CASP1CA1CA2CA7 | |
| SCHEMBL8427417 | 0.77 | TDP1 (0.58) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL9464191 | 0.76 | TDP1 (0.70) | TDP1LPAR1ADRB2ADRB1ADRB3 | |
| SCHEMBL9566300 | 0.75 | PTGER4 (0.43) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8696584 | 0.75 | PTGER4 (0.43) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8564144 | 0.75 | KMT2A (0.51) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL8567729 | 0.75 | KMT2A (0.51) | CA1CA2CA7CA9KMT2A | |
| SCHEMBL3650168 | 0.74 | TDP1 (0.78) | TDP1KMT2AAPPMAPTFFAR1 | |
| SCHEMBL304176 | 0.74 | TDP1 (0.78) | TDP1CASP1KMT2AAPPMAPT | |
| SCHEMBL29053751 | 0.73 | TDP1 (0.66) | TDP1LPAR1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827868-A | Prostaglandin analogs | E. R. SQUIBB & SONS, INC. (US) | 1998-10-27 | — | — | US | disclosed |