Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225361 | 0.81 | HPGD (0.50) | ALDH1A1LMNAMCOLN3HPGDTSHR | |
| Hydrochloric Acid SCHEMBL7298300 | 0.80 | HPGD (0.49) | ALDH1A1LMNAMCOLN3HPGDTSHR | |
| SCHEMBL8696361 | 0.76 | CTSS (0.50) | ALDH1A1LMNAKMT2ANPY5R | |
| SCHEMBL7468069 | 0.74 | PPARG (0.64) | ALDH1A1TSHRALOX15SMN1; SMN2POLB | |
| SCHEMBL5622664 | 0.73 | SMN1; SMN2 (0.64) | ALDH1A1TSHRALOX15SMN1; SMN2POLB | |
| SCHEMBL5442531 | 0.70 | HIF1A (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL28243675 | 0.70 | HIF1A (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL14796802 | 0.70 | HIF1A (0.55) | ALDH1A1HPGDSMN1; SMN2MAPTPOLB | |
| SCHEMBL8701236 | 0.69 | HPGD (0.55) | ALDH1A1LMNAMCOLN3HPGDTSHR | |
| SCHEMBL9225350 | 0.69 | TSHR (0.54) | ALDH1A1LMNAMCOLN3HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |