Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697744 | 0.95 | TACR3 (0.42) | POLBTACR3ALDH1A1GPR88CNR2 | |
| SCHEMBL3368388 | 0.89 | AOC3 (0.42) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL5640387 | 0.82 | LMNA (0.46) | POLBALDH1A1KDM4E | |
| SCHEMBL10349304 | 0.80 | POLB (0.47) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL14533617 | 0.78 | POLB (0.46) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL19286307 | 0.78 | POLB (0.46) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL4321786 | 0.77 | ACP3 (0.45) | ALDH1A1CNR2 | |
| SCHEMBL11357814 | 0.77 | POLB (0.49) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL8861456 | 0.77 | AOC3 (0.51) | POLBTACR3ALDH1A1KDM4EGPR88 | |
| SCHEMBL894067 | 0.76 | POLB (0.56) | POLBTACR3ALDH1A1KDM4EGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |