Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10130976 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL28388882 | 0.75 | PRSS1 (0.44) | ALDH1A1ADRA1DADRA1AADRA1BCYP1A2 | |
| SCHEMBL11075658 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ADRA1DADRA1AADRA1BCYP2D6 | |
| SCHEMBL9033324 | 0.72 | SIGMAR1 (0.40) | ALDH1A1SLC6A4ADRA1DADRA1AADRA1B | |
| SCHEMBL24025437 | 0.72 | ALDH1A1 (0.38) | ALDH1A1ADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL16901817 | 0.71 | ALDH1A1 (0.40) | ALDH1A1ADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL158329 | 0.71 | — | — | |
| SCHEMBL7357004 | 0.71 | ALDH1A1 (0.37) | ALDH1A1ADRA1DADRA1AADRA1BHTR2A | |
| SCHEMBL29020313 | 0.71 | ALDH1A1 (0.44) | ALDH1A1ADRA1DADRA1AADRA1BCHRM2 | |
| SCHEMBL7357007 | 0.69 | ALDH1A1 (0.41) | ALDH1A1ADRA1DADRA1AADRA1BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |