SCHEMBL8701399

SCHEMBL8701399

CN(C)c1cc(CCC(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
HSPA5 P11021 2/20 0.41
TSHR P16473 2/20 0.41
GAA P10253 1/20 0.41
CYP1A2 P05177 3/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 5/20 0.40
CYP2C9 P11712 4/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
HIF1A Q16665 3/20 0.40
CA2 P00918 3/20 0.37
CA1 P00915 2/20 0.37
HSD17B10 Q99714 1/20 0.36
POLB P06746 1/20 0.36
TYR P14679 1/20 0.36
NR1H4 Q96RI1 1/20 0.35
MAPT P10636 2/20 0.34
MAPK1 P28482 2/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29059477 0.80 HSPA5 (0.46) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL1535843 0.78 CA2 (0.58) ALDH1A1LMNATSHRGAACYP1A2
SCHEMBL10649238 0.72 CYP2C9 (0.59) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL2741315 0.70 ALDH1A1 (0.55) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL430927 0.69 CA2 (0.57) ALDH1A1HSPA5TSHRCYP2D6CYP2C19
SCHEMBL19124267 0.68 CYP2D6 (0.39) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL19130447 0.68 CYP1A2 (0.44) ALDH1A1LMNATSHRGAACYP1A2
SCHEMBL28674173 0.67 HSPA5 (0.60) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL466567 0.66 CYP2C19 (0.50) ALDH1A1LMNAHSPA5TSHRGAA
SCHEMBL29558774 0.66 HSPA5 (0.78) ALDH1A1LMNAHSPA5TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412302-A Poly (meth) acrylate functionalized resins as coagents for crosslinking thermoplastic polymers 阿科玛法国公司 2021-09-17 CN disclosed
US-5776294-A CROSSLINKED WITH METAL SALT OF AN UNSATURATED ACID SARTOMER COMPANY (US) 1998-07-07 US disclosed
US-5696190-A CURABLE ELASTOMERS MIXED WITH AN ACID SALT OF (DI)ALKYLAMINOALKYL PHENOL SARTOMER COMPANY (US) 1997-12-09 US disclosed
EP-0570277-B1 Method for adhering an elastomeric composition to a polar surface SARTOMER CO INC (US) 1995-12-13 EP disclosed
EP-0570277-A1 Method for adhering an elastomeric composition to a polar surface SARTOMER COMPANY, INC. (US) 1993-11-18 EP disclosed
EP-0487397-A1 Curable compositions and their use for obtaining cured elastomers SARTOMER COMPANY, INC. (US) 1992-05-27 EP disclosed