Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922833 | 0.80 | HSPA5 (0.68) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL8701399 | 0.80 | ALDH1A1 (0.41) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL11673514 | 0.79 | HSPA5 (0.43) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL28404083 | 0.79 | HSPA5 (0.56) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL11675110 | 0.77 | HSPA5 (0.48) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL39962 | 0.75 | CA2 (0.70) | CYP2C9CYP2C19HIF1ASMN1; SMN2CA2 | |
| SCHEMBL25995157 | 0.75 | ALOX5 (0.43) | CYP2C9CYP2C19HIF1ASMN1; SMN2TYR | |
| SCHEMBL2741315 | 0.75 | ALDH1A1 (0.55) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| SCHEMBL430927 | 0.74 | CA2 (0.57) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 | |
| Propane SCHEMBL28487756 | 0.73 | CA2 (0.61) | HSPA5CYP2C9CYP2C19HIF1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |