Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | CMA1 | P23946 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833842 | 0.83 | CYP4F2 (0.49) | ALDH1A1KDM4ELMNAMMP9CYP4F2 | |
| SCHEMBL3783310 | 0.77 | PKM (0.36) | CYP1A2CYP2C9ALDH1A1KDM4ELMNA | |
| SCHEMBL7847479 | 0.75 | CA2 (0.47) | ALDH1A1LMNA | |
| SCHEMBL13360707 | 0.71 | POLB (0.51) | ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL13360704 | 0.71 | KMT2A (0.52) | ALDH1A1LMNAHSD17B10CYP4F2CYP4A11 | |
| SCHEMBL11509480 | 0.71 | CA2 (0.52) | ALDH1A1KDM4ELMNASMN1; SMN2HPGD | |
| SCHEMBL6628783 | 0.71 | TSHR (0.55) | ALDH1A1KDM4ELMNATSHRSMN1; SMN2 | |
| SCHEMBL5653139 | 0.70 | CYP3A4 (0.47) | CYP1A2CYP2C9ALDH1A1KDM4ELMNA | |
| SCHEMBL13360687 | 0.70 | KMT2A (0.55) | ALDH1A1SMN1; SMN2GAACYP3A4CYP2C19 | |
| SCHEMBL5653955 | 0.70 | F2 (0.37) | CYP1A2CYP2C9ALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |