Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8309401 | 0.82 | TBXAS1 (0.52) | TBXAS1ALDH1A1LMNANLRP3 | |
| SCHEMBL8703687 | 0.81 | TBXAS1 (0.57) | TBXAS1ALDH1A1LMNA | |
| SCHEMBL8308559 | 0.81 | TBXAS1 (0.58) | TBXAS1 | |
| SCHEMBL8707364 | 0.80 | LTA4H (0.43) | TBXAS1LTA4HLMNASMN1; SMN2HTT | |
| SCHEMBL16508902 | 0.79 | TBXAS1 (0.57) | TBXAS1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8308276 | 0.79 | TBXAS1 (0.49) | TBXAS1 | |
| SCHEMBL8702343 | 0.79 | TBXAS1 (0.47) | TBXAS1 | |
| SCHEMBL8309224 | 0.75 | CYP3A4 (0.48) | TBXAS1 | |
| SCHEMBL8704645 | 0.73 | TBXAS1 (0.69) | TBXAS1LMNATP53 | |
| SCHEMBL8706682 | 0.73 | TBXAS1 (0.70) | TBXAS1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5705523-A | THROMBOXANE A2 SYNTHETASE INHIBITORS | PFIZER INC. (US) | 1998-01-06 | — | — | US | disclosed |